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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BRF1 All Species: 21.82
Human Site: S519 Identified Species: 36.92
UniProt: Q92994 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.23
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92994 NP_001510.2 677 73840 S519 R R E P I Q A S T A R E A I E
Chimpanzee Pan troglodytes XP_510208 819 88957 S661 R R E P I Q A S T A R E A I E
Rhesus Macaque Macaca mulatta XP_001098066 599 65136 E448 S T A R E A I E K M L E Q K K
Dog Lupus familis XP_548005 637 70371 I486 A S T A G E A I E K M L E Q K
Cat Felis silvestris
Mouse Mus musculus Q8CFK2 676 73781 S518 R R E P I L A S T A G E A I E
Rat Rattus norvegicus NP_001100231 686 74096 S528 R R E P I L A S T A G E A I E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421405 681 75256 S524 K R E P I Q A S T A G E A I E
Frog Xenopus laevis NP_001088063 660 73751 A506 R K P S K R R A P I Q A S T A
Zebra Danio Brachydanio rerio NP_956183 693 76806 S525 K R E P I L A S T A G E A I E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650616 662 73627 E511 S T A G E A I E K M L Q E K K
Honey Bee Apis mellifera XP_623775 648 73504 T497 K S Q A P A N T A G E A I E K
Nematode Worm Caenorhab. elegans NP_495526 759 84015 D555 S I K V D S S D V T P D T L S
Sea Urchin Strong. purpuratus XP_794011 768 83924 N588 K K P P I Q A N T A G E A I E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P29056 596 66888 L445 C P R N L H L L P T T D T Y L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.3 86.4 82.7 N.A. 89.8 81.6 N.A. N.A. 78.1 72.5 65.9 N.A. 42.5 43.4 32.4 46.3
Protein Similarity: 100 80 87 85.9 N.A. 93.3 86 N.A. N.A. 87 84.7 77.6 N.A. 59.6 61.7 50 60.1
P-Site Identity: 100 100 6.6 6.6 N.A. 86.6 86.6 N.A. N.A. 86.6 6.6 80 N.A. 0 0 0 66.6
P-Site Similarity: 100 100 13.3 20 N.A. 86.6 86.6 N.A. N.A. 93.3 40 86.6 N.A. 13.3 26.6 26.6 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 45.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 15 15 0 22 58 8 8 50 0 15 50 0 8 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 0 8 0 0 0 15 0 0 0 % D
% Glu: 0 0 43 0 15 8 0 15 8 0 8 58 15 8 50 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 8 8 0 0 0 0 8 36 0 0 0 0 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 50 0 15 8 0 8 0 0 8 50 0 % I
% Lys: 29 15 8 0 8 0 0 0 15 8 0 0 0 15 29 % K
% Leu: 0 0 0 0 8 22 8 8 0 0 15 8 0 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 15 8 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 8 8 0 0 0 0 0 0 0 % N
% Pro: 0 8 15 50 8 0 0 0 15 0 8 0 0 0 0 % P
% Gln: 0 0 8 0 0 29 0 0 0 0 8 8 8 8 0 % Q
% Arg: 36 43 8 8 0 8 8 0 0 0 15 0 0 0 0 % R
% Ser: 22 15 0 8 0 8 8 43 0 0 0 0 8 0 8 % S
% Thr: 0 15 8 0 0 0 0 8 50 15 8 0 15 8 0 % T
% Val: 0 0 0 8 0 0 0 0 8 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _